The immunoproteasome regulates ILC2 responses by modulating mitochondrial capability

Lawsuits of the National Academy of Sciences, Volume 122, Disaster 47, November 2025.
SignificanceProteasomes degrade poly-ubiquitinylated proteins. Inhibition of the constitutively expressed proteasome is toxic to cells. Immune cells particular an immunoproteasome whose expression relative to the constitutive proteasome increases with their …
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