We get another doubleheader for Monday Night Football in Week 6, with the Bills visiting the Falcons at 7:15 p.m., followed by the Commanders hosting the Bears an hour later.

The Bills opened as road favorites, while the MNF odds have the Commanders sitting at -4.5. Follow here for the latest Monday Night Football odds, MNF player props, and the full NFL Monday schedule for 2025.

Monday Night Football odds

Bills vs Falcons odds

Bills vs Falcons opening odds

Point spread: Bills -3.5 | Falcons +3.5
Moneyline: Bills -205 | Falcons +170
Total: Over 48.5 | Under 48.5

Bears vs Commanders odds

Bears vs Commanders opening odds

Point spread: Bears +4.5 | Commanders -4.5
Moneyline: Bears +185 | Commanders -225
Total: Over 50.0 | Under 50.0

Bills vs Falcons player props

Bills vs Falcons touchdown props

More Bills vs Falcons picks from Covers

Bears vs Commanders player props

Bears vs Commanders passing props

View all MNF passing props, including Caleb Williams odds and Jayden Daniels odds.

Bears vs Commanders rushing props

View all MNF rushing props, including D’Andre Swift odds and Jacory Croskey-Merritt odds.

Bears vs Commanders receiving props

View all MNF receiving props, including Rome Odunze odds and Terry McLaurin odds.

Bears vs Commanders touchdown props

More Bears vs Commanders picks from Covers

Monday Night Football 2025 schedule & how to watch

Date	Matchup	Time
9/8 Week 1	Vikings (27) at Bears (24)	8:15 ESPN/ABC
9/15 Week 2	Buccaneers (20) at Texans (19)	7:00 ESPN/ABC
9/15 Week 2	Chargers (20) at Raiders (9)	10:00 ESPN
9/22 Week 3	Lions (38) at Ravens (30)	8:15 ESPN/ABC
9/29 Week 4	Jets (21) at Dolphins (27)	7:15 ESPN
9/29 Week 4	Bengals (3) at Broncos (28)	8:15 ABC
10/6 Week 5	Chiefs (28) at Jaguars (31)	8:15 ESPN/ABC
10/13 Week 6	Bills at Falcons	7:15 ESPN
10/13 Week 6	Bears at Commanders	8:15 ABC
10/20 Week 7	Buccaneers at Lions	7:00 ESPN/ABC
10/20 Week 7	Texans at Seahawks	10:00 ESPN+
10/28 Week 8	Commanders at Chiefs	8:15 ESPN/ABC
11/3 Week 9	Cardinals at Cowboys	8:15 ESPN/ABC
11/10 Week 10	Eagles at Packers	8:15 ESPN/ABC
11/17 Week 11	Cowboys at Raiders	8:15 ESPN/ABC
11/24 Week 12	Panthers at 49ers	8:15 ESPN
12/1 Week 13	Giants at Patriots	8:15 ESPN
12/8 Week 14	Eagles at Chargers	8:15 ESPN/ABC
12/15 Week 15	Dolphins at Steelers	8:15 ESPN
12/22 Week 16	49ers at Colts	8:15 ESPN
12/29 Week 17	Rams at Falcons	8:15 ESPN
	No MNF matchup for Week 18

MNF betting tips

From Jason Logan, Covers Senior Industry Analyst

Time to heal

The polar opposite of one of my TNF betting tips, Monday games leave players with more time to nurse any wounds. Injured players have an extra day for recovery and often will wait until the 11th hour to make a decision.

What happens next?

Monday games present a shorter schedule for the teams involved, falling one day behind the usual cadence in preparing for the upcoming week. While not as drastic as navigating a Thursday game, teams may have to forfeit either an early-week walkthrough or a rest day in order to stay on schedule. Look at the teams’ upcoming schedule and see if this later finish week leads to more problems ahead — especially for the road team, which also needs to factor in travel.

Home-field frenzy

The veracity of the home can get ramped up on prime-time games. Instead of the usual tailgating duration for a 1 p.m. or 4 p.m. game, the home crowd instead gets to party all day long. That juiced-up crowd is then released into the stadium — and unleashed onto the visitors — giving the home hospitality a little extra bite.

Cold concerns

Monday nighters can also be an advantage for cold weather teams come December and January. Temperatures plummet when the sun goes down and places like Buffalo, Foxborough, and East Rutherford can turn into frozen wastelands. While both sides feel the chill of the low temps, visitors from warmer cities or indoor stadiums may struggle to adapt when the mercury drops.

FREE NFL PICKS

This article originally appeared on Covers.com, read the full article here

Monday Night Football Odds: MNF Betting Lines 2025